Validated Model · Operational Foundation · Clinical Evidence

Proof of Concept

Our model is not theoretical. It is validated by real-world deployment data, built on an existing operational foundation, and supported by a named clinical advisory board.

Proof 1 of 3

🇮🇳 India: This already works at scale.

India is the operational proof of concept for the exact model Mandiera is building in Africa — government-partnered, nurse-operated, mobile-first, mass community deployment, validated at scale.

380,000+
iBreastExam scans performed
22
Government hospital partners in Maharashtra alone
5
State government partnerships
86–88%
Validated device accuracy
"iBreastExam has been validated as a potential powerful screening tool which can distinguish between hard and soft tissues with great sensitivity and specificity."
— Government Medical College, Nagpur, Maharashtra

Source: UE LifeSciences public coverage and peer-reviewed clinical studies. Full bibliography available in Series A pitch deck.

Proof 2 of 3

🇿🇦 Vision World SA: The fire is already burning.

We are not asking investors to fund a concept. We are asking them to fuel a model that is already working through our operational base at Vision World SA.

✅ HPCSA-Registered Practitioners

All practitioners registered with the Health Professions Council of South Africa — recognised and reimbursed by medical aid schemes. Zero gap to cancer screening reimbursement.

✅ Medical Aid Billing — Live

Zero cost to employer or employee. Medical aids already pay us. This is the exact billing model Mandiera HealthTech scales across 10 schemes and 5 countries.

✅ Named Corporate Clients

Multiple large South African corporates already served. Available for investor due diligence and verification.

✅ Health Trend Reports Delivered

Anonymised workforce health trend reports already produced and delivered to corporate clients — the MedIntelligence™ / MCRI™ concept in practice today.

✅ Practitioner Network Operational

GPs, specialists, registered nurses, dieticians — contracted and operating. The clinical team exists. It is not on a hiring wishlist.

✅ Multi-Province Presence

Geographic diversity already demonstrated. Operational reach extends across multiple South African provinces today.

"Series A is the gasoline to blow this up continent-wide — not the match to start the fire. The fire is already burning."
Proof 3 of 3

📊 The Basepaws Precedent: The database is worth more than the business.

2019

Basepaws pitches cat DNA testing on Shark Tank. Valuation: ~$2.5M. Kevin O'Leary invests $125K.

2022

Zoetis — an $80B animal health company — acquires Basepaws for ~$93M. O'Leary's $125K becomes ~$4.5M.

37×

Revenue multiple paid. The asset Zoetis purchased was not the device. It was the genomic database.

Basepaws built a cat DNA database. Zoetis paid $93M for it.

Mandiera is building a human cancer intelligence database across 1.4 billion Africans.

The acquirer of Mandiera will not be buying a screening company. They will be buying Africa's cancer intelligence infrastructure. The scarcity premium on that asset has no ceiling.

Clinical Device Credentials

FDA-Cleared

iBreastExam Class II. 510(k) clearance. USA standard.

🔄

SAHPRA Filing

Registration in progress . . .

CE Marked

European conformity. Medical device standard.

ISO 13485

Medical device quality management. Manufacturing certified.

Note: SAHPRA device registration is in progress and expected to complete within 3–4 months of filing. FDA Class II clearance and CE marking, under SAHPRA's harmonisation framework, accelerates the SA registration process. Commercial deployment in South Africa commences upon SAHPRA approval.